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This article contains details about an upcoming season.
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- Diane Guerrero as Jane/Crazy Jane
- April Bowlby as Gertrude Cramp/Rita Farr/Elasti-Woman
- Joivan Wade as Vic Stone/Cyborg
- Riley Shanahan and Brendan Fraser as Cliff Steele/Robotman
- Matthew Zuk and Matt Bomer as Larry Trainor/Negative Man
- Timothy Dalton as Dr. Niles Caulder/Chief
- Abigail Shapiro as Dorothy Spinner